Cozy Mac and Cheese Meatloaf Casserole Recipe for Family Dinner

Comfort food reaches new heights with this mac and cheese meatloaf casserole that blends two classic dishes into one incredible meal.

Hearty ground beef mingles with creamy pasta and melted cheese, creating a satisfying dinner that promises to become a household favorite.

Layers of rich flavors stack together in a harmonious blend of textures and tastes.

Each forkful delivers a perfect combination of tender meat and cheesy pasta goodness.

The recipe combines simple ingredients with straightforward preparation, making it an excellent choice for busy weeknight dinners.

Families will love this delicious twist on traditional meatloaf that brings extra excitement to the dinner table.

Prepare to savor every delectable bite of this irresistible comfort food masterpiece.

Tips For Juicy Meatloaf & Creamy Mac

  • Use Ritz Crackers for a lighter, more tender meatloaf that keeps the meat moist and adds a subtle buttery flavor.
  • Mix in sauce and eggs to help bind ingredients and maintain moisture throughout the cooking process.
  • Whisk milk and condensed soup until smooth to create a creamy, lump-free sauce that coats macaroni evenly.
  • Spread macaroni mixture carefully over meatloaf to ensure even distribution and consistent flavor in every bite.
  • Allow casserole to sit for a few minutes after baking to help cheese set and make cutting and serving easier.

Variations For Your Favorite Mashup

  • Gluten-Free Meatloaf Casserole: Replace Ritz Crackers with gluten-free breadcrumbs or crushed gluten-free corn flakes. Use gluten-free onion soup mix and verify all sauce ingredients are gluten-free.
  • Vegetarian Mac and Cheese Bake: Swap ground beef with plant-based ground meat or lentils. Use vegetable broth instead of meat-based ingredients. Add extra seasonings for robust flavor.
  • Low-Carb Cauliflower Version: Substitute macaroni with riced cauliflower or cauliflower florets. Reduce condensed soup and use heavy cream for creaminess. Add extra cheese for texture.

Serving Up Mac & Cheese Meatloaf Casserole

  • Comfort Food Companions: Crisp green salad with tangy vinaigrette balances the rich, hearty casserole.
  • Bread Buddy: Warm garlic toast or crusty French bread provides perfect sauce-soaking opportunities.
  • Veggie Vibrancy: Roasted broccoli or honey-glazed carrots add nutritious color and complementary flavors to the dish.
  • Cool Contrast: Creamy coleslaw with a zesty kick offers refreshing contrast to the warm, cheesy meatloaf.

Storing Cheesy Casserole For Later Meals

  • Store leftovers in an airtight container within 2 hours of cooking. Keep in the refrigerator for up to 3-4 days. Place the casserole in a sealed container or wrap tightly with plastic wrap or aluminum foil.
  • Transfer cooled casserole to a freezer-safe container or freezer bag. Remove excess air and seal completely. Freeze for up to 2-3 months. Label with the date and contents.
  • Preheat oven to 350F. Cover casserole with aluminum foil to prevent drying. Warm for 15-20 minutes until heated through. Check internal temperature reaches 165F for food safety.
  • Place individual portions on a microwave-safe plate. Heat in 30-second intervals, stirring between each interval.

FAQs

  • Can I use ground turkey instead of ground beef?

Yes, ground turkey is a great lean alternative that works well in this recipe. Just ensure it’s fully cooked and seasoned similarly to maintain flavor.

  • Is Ritz crackers necessary for the meatloaf?

Ritz crackers help bind the meatloaf and add subtle richness. If unavailable, you can substitute with breadcrumbs or crushed saltine crackers without significantly changing the texture.

  • Can I make this recipe ahead of time?

You can prepare the meatloaf mixture and mac and cheese separately, refrigerate, and assemble just before baking. Alternatively, fully assemble and refrigerate, then bake when ready to serve.

Mac And Cheese Meatloaf Casserole: The Mashup

  • Transform classic meatloaf and mac and cheese into a mouthwatering one-dish wonder that brings excitement to dinnertime.
  • Combine two beloved favorites for a guaranteed hit that satisfies both kids and adults with its rich, cheesy, meaty goodness.
  • Minimal prep work and straightforward ingredients make this recipe accessible for home cooks of all skill levels, delivering maximum flavor with minimal effort.
  • Perfect for family gatherings, weeknight meals, or potluck events where you want to impress without spending hours in the kitchen.

All The Cheesy, Savory Ingredients For The Casserole

Meat Base:
  • Ground Beef: A hearty protein that forms the foundation of the meatloaf.
  • Ritz Crackers: Provides texture and helps bind the meat mixture together.
  • Lipton Onion Soup Mix: Adds deep flavor and seasoning to the meat.
  • Eggs: Acts as a binding agent to hold the meatloaf ingredients together.
Sauce Components:
  • Ketchup, Barbecue Sauce: Creates a tangy and sweet coating for the meatloaf.
Cheese and Dairy:
  • Condensed Cheddar Cheese Soup, Shredded Cheese: Delivers rich, creamy cheese flavor to the casserole.
  • Milk: Helps create a smooth and creamy macaroni mixture.
Pasta Component:
  • Macaroni Noodles: Provides the classic pasta base for the cheesy topping.
Seasoning Blend:
  • Salt, Pepper, Garlic Powder, Onion Powder: Enhances the overall flavor profile of the dish.

Casserole Tools For A Cheesy Bake

  • Large mixing bowls: Essential for combining meat and macaroni ingredients smoothly.
  • 9×13 inch baking dish: Perfect for layering meatloaf and mac and cheese.
  • Whisk: Great for blending milk and condensed cheese soup without lumps.
  • Measuring cups: Crucial for accurate ingredient proportions.
  • Colander: Needed to drain cooked macaroni noodles.
  • Wooden spoon or spatula: Helps mix ingredients and spread layers evenly.
  • Cheese grater: Useful if using block cheese instead of pre-shredded.

Building Mac & Cheese Meatloaf Casserole Layers

Step 1: Warm Up the Oven

Crank the oven to a toasty 350F (175C).

Grab a 9×13 inch baking dish and give it a generous coating of cooking spray or butter to prevent sticking.

Step 2: Create the Sauce Blend

In a medium bowl, swirl together ketchup and barbecue sauce until they’re best friends.

Set this flavor-packed mixture aside for later.

Step 3: Build the Meaty Foundation

Grab a large mixing bowl and plop in the ground beef.

Crush Ritz Crackers into tiny pieces and sprinkle them over the meat.

Shake in the Lipton onion soup mix.

Crack in some eggs.

Pour half of the sauce mixture into the bowl.

Get your hands dirty and mix everything until it’s completely combined.

Press the mixture into the baking dish like you’re making a delicious meat canvas.

Drizzle the remaining sauce on top for extra flavor.

Step 4: First Baking Round

Send the meatloaf into the oven for 30 minutes.

While it’s cooking, boil the macaroni noodles according to the package instructions, then drain them in a colander.

Step 5: Cheese Sauce Magic

In a large bowl, whisk milk and condensed cheddar cheese soup until silky smooth.

Sprinkle in:
  • Salt
  • Pepper
  • Garlic powder
  • Onion powder

Fold in the cooked macaroni and two cups of shredded cheese.

Step 6: Final Assembly and Bake

Pull the meatloaf out of the oven.

Carefully pour the cheesy macaroni mixture over the top, spreading it evenly.

Shower the top with the remaining cheese.

Slide back into the oven for 17-20 minutes until the cheese turns golden and bubbly.

Let it rest for a few minutes before diving in.

Print
clock clock iconcutlery cutlery iconflag flag iconfolder folder iconinstagram instagram iconpinterest pinterest iconfacebook facebook iconprint print iconsquares squares iconheart heart iconheart solid heart solid icon

Mac and Cheese Meatloaf Casserole Recipe


5 Stars 4 Stars 3 Stars 2 Stars 1 Star

4.5 from 27 reviews

  • Total Time: 1 hour 10 minutes
  • Yield: 8 1x

Description

Classic mac and cheese meatloaf casserole delivers comfort food perfection in one hearty dish. Cheese-laden layers combine ground beef, pasta, and creamy sauce for a satisfying meal you’ll crave again and again.


Ingredients

Scale

Main Ingredients:

  • 2 lbs lean ground beef
  • 3 cups macaroni noodles
  • 4 cups shredded mozzarella and cheddar cheese blend
  • 2 cups milk
  • 10.5 ounces (298 grams) condensed cheddar cheese soup

Seasoning and Flavoring Ingredients:

  • 2 ounces (57 grams) Lipton onion soup mix
  • 1 tablespoon garlic powder
  • 1 tablespoon onion powder
  • 1 teaspoon salt
  • 1 teaspoon pepper
  • 2 eggs
  • 30 Ritz Crackers

Sauce and Topping Ingredients:

  • 1 cup ketchup
  • 1 cup Sweet Baby Rays Hickory & Brown Sugar barbecue sauce

Instructions

  1. Warm the oven to 350F (175C) and lightly coat a 9×13 inch baking vessel with cooking spray.
  2. Craft a tangy glaze by whisking ketchup and barbecue sauce in a medium bowl. Reserve for later use.
  3. Combine ground beef with crushed Ritz crackers, Lipton onion soup mix, and eggs in a large mixing bowl. Incorporate half the prepared sauce and thoroughly blend ingredients. Transfer the meat mixture into the prepared baking dish, creating an even layer. Generously drizzle remaining sauce across the surface.
  4. Roast the meatloaf for 30 minutes. Simultaneously, cook macaroni according to package instructions and drain completely.
  5. Whisk milk and condensed cheddar cheese soup until silky smooth. Season with salt, pepper, garlic powder, and onion powder. Fold in cooked macaroni and two-thirds of the shredded cheese.
  6. Extract meatloaf from oven and carefully spread macaroni mixture over the surface. Scatter remaining cheese across the top. Return to oven and bake 17-20 minutes until cheese melts and develops golden edges. Allow casserole to rest briefly before serving.

Notes

  • Customize Meat Blend by swapping ground beef with ground turkey or plant-based alternatives for healthier protein options.
  • Control Sodium by using low-sodium Ritz crackers and reduced-sodium onion soup mix to make the dish more heart-friendly.
  • Enhance Flavor Depth by adding fresh herbs like chopped parsley or thyme into the meat mixture for extra aromatic complexity.
  • Make Gluten-Free by substituting Ritz crackers with gluten-free breadcrumbs and checking that all other ingredients are gluten-free certified.
  • Prep Time: 20 minutes
  • Cook Time: 50 minutes
  • Category: Dinner, Snacks
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 8
  • Calories: 445
  • Sugar: 12 g
  • Sodium: 920 mg
  • Fat: 24 g
  • Saturated Fat: 11 g
  • Unsaturated Fat: 9 g
  • Trans Fat: 0 g
  • Carbohydrates: 36 g
  • Fiber: 1 g
  • Protein: 25 g
  • Cholesterol: 95 mg
Marcus Reed

Marcus Reed

Founder & Food Content Creator

Expertise

Single-recipe development, Seasonal and local ingredient utilization, Food photography and styling, Culinary writing and content creation​

Education

Culinary Arts Certificate, Blue Ridge Community and Technical College, WV
Focus: Fundamentals of culinary techniques, emphasizing hands-on experience in small-scale kitchen settings.


Marcus’s story begins in Asheville, where good food and family kitchens shaped his earliest memories. After hands-on culinary training and a lot of trial (and a little error), he realized that real cooking isn’t about perfection, it’s about connection.
At Pan and Oven, Marcus crafts recipes that are easy to follow, packed with flavor, and built for real kitchens.

Leave a Reply

Your email address will not be published. Required fields are marked *

Recipe rating 5 Stars 4 Stars 3 Stars 2 Stars 1 Star